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South Africa is dedicated to attaining Universal Health Coverage via the National Health Insurance program, with the NHI Bill set to be enacted into law in 2024. The primary healthcare system, essential for Universal Health Coverage delivery, encounters ongoing challenges such as a shortage of healthcare professionals, insufficient infrastructure and medication shortages, financial limitations, and inadequate governance frameworks. The Johannesburg health district has experienced high turnover among trained primary healthcare nurses over the past two financial years, leading to staff shortages and decreased morale. This situation threatens the achievement of Universal Health Coverage. Additionally, patients were often turned away from primary health facilities due to early closures and staff shortages, limiting access to healthcare and hindering UHC goals. To achieve UHC, healthcare services must be available, accessible, affordable, and of high quality.To explore the experiences of professional nurses with regards to the implementation of Universal Health Coverage at Primary Health Care facilities in the Johannesburg health district, Gauteng. A qualitative, exploratory, descriptive methodology was employed. Eleven participants, comprising operational managers, professional nurses, and an area manager, were purposefully selected from eight primary healthcare facilities in Regions C and G of Johannesburg. Semi-structured interviews were performed, audio-recorded, and thematically evaluated using Braun & Clarke’s framework. Three themes emerged: (1) Hhuman resource limitations and professional erosion including staff shortages and high turnover, (2) healthcare system inadequacies  and patient accessibility such as poor infrastructure and medication stockouts; and (3) financial and policy constraints that impede effective UHC implementation. Nurses' experiences indicate structural obstacles hindering the implementation of UHC. It is essential to address personnel shortages, infrastructure deficiencies, and policy inefficiencies. Enhancing governance and prioritising nurse involvement in policymaking are crucial for attaining equitable, high-quality healthcare in South Africa.