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During the pandemic and post-pandemic of Covid-19, MSMEs are required to continue to survive, and even compete at the regional and global level. The improvement of technology and resources need to be optimized. The purpose of this study is to examine and analyze: (1) the influence of Attitudes toward Information and Communications Technology (ICT) and Mimetic Isomorphism partially on Strategic Management in Islamic Perspective (SMIP); (2) the moderating role of Qur’anic Work Ethics (QWE) in the relationship between Attitudes toward ICT and SMIP; (3) the moderating role of Qur’anic Work Ethics (QWE) in the relationship between Mimetic Isomorphism and SMIP. This study is conducted in Batik MSMEs in Pekalongan with the number of respondents of 154 MSMEs. The primary data is collected through purposive sampling using a questionnaire. The results of this study show that: (1) there is a partial influence of Attitudes toward ICT and Mimetic Isomorphism on SMIP; (2) there is a moderating role of QWE in the relationship between Attitudes toward ICT and SMIP; and (3) there is a moderating role of QWE in the relationship between Mimetic Isomorphism and SMIP.