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This paper reviews existing literature on the United States of America (USA) mediation in the Israel and Palestine conflict under Donald J Trump's Presidency during his first term of office. The review flows from an expansive point of view to a narrow point of view. The expansive point of view will deal with the term mediation, what mediation entails, and other factors revolving around the causes of successful and failed mediation procedures. Thus, this narrowed point of view will focus on the USA mediation in the Israel and Palestine conflict during the first term of Donald Trump in the Oval Office. Therefore, by employing a qualitative research methodology, the paper reviews data from existing journal articles, books, and governmental reports on the use of mediation as a means of diplomacy in the Middle East conflict during Trump's administration. The findings of the paper suggest that in the first administration of Trump, the USA was using mediation as a weapon to advance their national interests while also fostering their international dominance. Hence, the paper concludes that mediation can be used as an example of foreign policy aspirations of a state which can be weaponised to advance the state's internal interest.