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The Covid-19 pandemic, a catalyst in embracing the online mode of learning, is one of the key motivating factors for a paradigm shift in curriculum development due to the increased focus and reliance on technology. For the effective education of tertiary students globally, a revised curriculum development integrated with the Learning Management Systems and other eLearning platforms or tools that support asynchronous learning play a key role. This study seeks to determine the influence of user experience and user interface design of e-learning platforms on learning experience in higher education. A systematic review of studies regarding usability of e-learning platforms at tertiary institutions was conducted to determine the common issues and successes. A snapshot of research over the last five years was used in a systematic review to determine the influence of UX/UI on eLearning concerning higher education. Using the ERIC and Google scholar databases of journals, and specific criteria for selection of publications, 25 articles were examined in this study. Findings indicate that focused attention on interface design and user experience of eLearning systems for effective learning is crucial.