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Single motherhood is a prevalent phenomenon within low-resourced communities globally, especially within African communities. Despite the fact that discourses on single mothers have received considerable attention in social sciences, there remains a notable gap within social work literature where momentous traction is still needed. This thematic narrative literature review synthesises current evidence regarding the challenges faced by single mothers in low-resource communities across Africa. Employing a thematic approach to literature selection, the analysis found several key areas of hardship and economic instability. Further, the findings included childcare and educational barriers, health and under nutrition, limited social support and stigma for single mothers, lack of safety and protection from violence and crimes, as well as poor policy implementation and service access. These findings highlight a complex interaction among macroeconomic factors in African communities, discriminatory gender values and norms, and community service structures, which frequently intensify vulnerabilities for single mothers and their children. The recommendations made emphasises the need for policy and programme redesigns in African communities, advocating for community-based strategies that prioritise gender sensitivity and inclusivity to address the distinctive socioeconomic challenges encountered by single mothers in low-resource settings. Further, recommendations are made on establishing family-inclusive social frameworks that extend beyond marriage-based models to include strengthening of child support enforcement mechanisms and paternal responsibility legislation.