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Gauteng, South Africa's preeminent economic hub, confronts the imperative of achieving sustainable infrastructure development amidst rapid urbanization. The strategic integration of smart initiatives is crucial for fostering economic growth, environmental resilience, and societal well-being. This paper presents a critical review of Gauteng's infrastructure sustainability efforts through smart initiatives, employing a conceptual model that delineates Infrastructure Sustainability Development (ISD) as the dependent variable. Four independent variables—Smart Energy Systems, Smart Transportation, Smart Water Management, and Smart Urban Planning—are examined, each further defined by five sub-variables to ensure a comprehensive evaluation of their impact. This analysis evaluates the efficacy of provincial smart infrastructure initiatives, including the flagship Lanseria Smart City project, in promoting sustainability and aligning with the United Nations Sustainable Development Goals (SDGs). The study draws upon relevant theoretical frameworks, including Sustainable Development Theory, Systems Theory, Innovation Diffusion Theory, and the Smart Cities Framework, to provide a robust analytical foundation. The findings highlight achievements, challenges, and prospects, culminating in policy implications and recommendations for enhancing sustainable infrastructure development in Gauteng.