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With a lot of transformation in higher education, teaching, and learning is becoming very complex. To cope with the transformation that is so complex, academics must be innovative in their teaching. Their teaching should also influence the behaviour of their students. Students after completion of their studies must also be able to solve the challenges of society. There are several approaches to teaching and learning such as multidisciplinary, interdisciplinary, and ideally transdisciplinary, scholarship of teaching and learning, evidence-based teaching and learning, transdisciplinary teaching and learning and competence-based teaching and learning, and deep learning approaches among others. This paper focuses on the transdisciplinary research and teaching and learning approach. The aim of the paper is to investigate the importance of transdisciplinary research, teaching, and learning in a world that is faced with multifaceted challenges. This is a qualitative design paper where systemic desktop research was used. The systematic reviews follow structured and predefined methods to identify, appraise, and synthesise the relevant literature. Desktop research is a research method that involves the use of existing data. These are secondary collected and summarised data to increase the overall effectiveness of the investigation. Secondary research is much more cost-effective than primary research, as it uses existing data, unlike primary empirical research. The secondary literature was collected based on the history, challenges, and benefits of transdisciplinary research, teaching, and learning. The research study concludes that transdisciplinary research and teaching and learning approach is the way to go in solving constant challenges that face the world. The study recommends that university faculties, schools, and departments should engage in transdisciplinary teaching, and learning and research.

With a lot of transformation in higher education, teaching, and learning is becoming very complex. To cope with the transformation that is so complex, academics must be innovative in their teaching. Their teaching should also influence the behaviour of their students. Students after completion of their studies must also be able to solve the challenges of society. There are several approaches to teaching and learning such as multidisciplinary, interdisciplinary, and ideally transdisciplinary, scholarship of teaching and learning, evidence-based teaching and learning, transdisciplinary teaching and learning and competence-based teaching and learning, and deep learning approaches among others. This paper focuses on the transdisciplinary research and teaching and learning approach. The aim of the paper is to investigate the importance of transdisciplinary research, teaching, and learning in a world that is faced with multifaceted challenges. This is a qualitative design paper where systemic desktop research was used. The systematic reviews follow structured and predefined methods to identify, appraise, and synthesise the relevant literature. Desktop research is a research method that involves the use of existing data. These are secondary collected and summarised data to increase the overall effectiveness of the investigation. Secondary research is much more cost-effective than primary research, as it uses existing data, unlike primary empirical research. The secondary literature was collected based on the history, challenges, and benefits of transdisciplinary research, teaching, and learning. The research study concludes that transdisciplinary research and teaching and learning approach is the way to go in solving constant challenges that face the world. The study recommends that university faculties, schools, and departments should engage in transdisciplinary teaching, and learning and research.